They found that DKK2 expression in tumor cells led to enhanced liver metastasis and poor survival in mice. Mechanistically, they associate Dkk2-deficiency in donor AKP tumor organoids with reduced ...

Certain cancers can cause high white blood cell (WBCs) counts, or in some cases, low levels. WBCs, also called leukocytes, are immune system cells that fight pathogens in your body. A high white blood ...

What is sickle cell disease? Sickle cell disease (SCD) is an inherited blood disorder. That means it is passed down from a parent’s genes. It causes the body to make abnormal hemoglobin. Hemoglobin is ...

The aim of the present work is to evaluate the role of BMP9 and BMP10 in liver by depleting Bmp9 and Bmp10 from the main liver cell types (endothelial cells (EC), hepatic stellate cells (HSC), Kupffer ...

This paper presents a low power Clock Gating scheme for clock power improvement that reduces power dissipation by deactivating the clock signal to an inactive value (for clock gating cell) when clock ...

Clock Gating which is a deliberate power saving phenomenon functions to save dynamic power consumption in an SOC. Similar to other sequential cells timing requirements are also required to be met on ...

The inflammatory changes in asthma are driven by immune mechanisms, which are mediated by various immune cells. The T-cell subsets play an important role in this, and are the main source of ...