Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene ...

Data from Phase 2a study demonstrated the first clinical proof of concept for alpibectir in combination with ethionamide (AlpE) in the treatment ...

Tuberculosis (TB) remains one of the deadliest infectious diseases, claiming 1.5 million lives each year. Now, researchers have uncovered a surprising trick that helps explain its success: the ...

Existing treatments control TB and HIV, but the immune system does not revert to normal, helping explain why people living with HIV remain susceptible to infections and underscoring the need for ...

RESEARCHERS have developed a cutting-edge human lung-on-chip system, called iLoC, that could transform how clinicians and scientists study respiratory infections, including tuberculosis (TB). Unlike ...

Introduction Tuberculosis (TB) remains a critical global public health challenge, and there is an urgent need to improve the diagnosis and management of post-TB lung disease (PTLD). We aimed to ...

Tuberculosis (TB) remains a leading cause of infectious disease mortality globally. Its pathogenesis is now understood to be heavily shaped by immunometabolic perturbations and host comorbidities. In ...

Dr. Stephen Carpenter has always been interested in learning about the pathogenesis of disease, or how a disease develops. While in his first year of clinical medicine residency at NYU Langone Health, ...

After The Times published an interview with John Green about his new book on tuberculosis, many readers wrote to share their families’ history with the disease. Compiled by Stephanie Nolen Recently, ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. What we could not have imagined at the time was the sudden ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. The manuscript finds a ...