We examined alpha- and gamma-herpesvirus alterations to a type of alternative splicing, namely circular RNA (circRNA) synthesis. We developed “Circrnas in Host And viRuses anaLysis pIpEline” (CHARLIE) ...

Targovax ASA ( ($GB:0RIS) ) just unveiled an announcement. Circio Holding ASA has requested Atlas to subscribe and pay for an additional tranche ...

LncRNAs and circRNAs are key regulators of gene expression, influencing disease mechanisms and offering potential as ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The DREAM repressor complex regulates genes ...

Linear RNA is inherently unstable so using it in mRNA vaccines requires that the vaccines be stored and deployed in specific conditions to avoid degradation and loss of effectiveness, institute ...

Pancreatic cancer is one of the deadliest cancers. But those battling the disease saw promising results in the small clinical trial of an mRNA vaccine.

Together, we intend to accelerate the field of next-generation medicines in mRNA and CRISPR, using best-in-class chemistries, processes, and proprietary technologies like CleanCap ® analogs ...

A team at Memorial Sloan Kettering has been working to improve those outcomes by developing a new mRNA vaccine for pancreatic cancer. A few years ago, the team embarked on a small trial to test the ...

A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Viruses ...

Notably, some genetic variants specifically affect circRNA expression without altering the expression of their linear mRNA counterparts, suggesting that circRNAs may contribute uniquely to the genetic ...

The study found that the new mRNA vaccine was successful in triggering an immune defence response that helped to reduce TB numbers in infected mice. In addition, the researchers discovered that ...