Hierarchical communication between cells with distinct positional memories orchestrates the regeneration of missing limb structures in axolotls.

Identification of a nitric oxide-regulated transitional state of Müller glia reveals a key mechanism enabling neuronal regeneration in the injured vertebrate retina.

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

High-profile news coverage that eLife papers generated in October 2025, including NPR, One Earth and Neuroscience News.

Researchers have mapped the cellular diversity of the eye’s fluid drainage tissue, uncovering a cell subtype that may contribute to glaucoma progression and respond to vitamin B3 treatment.

CDK2-mediated TBK1 degradation via Dtx4 represents a previously unrecognized regulatory mechanism that modulates antiviral immunity in fish.

Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.