
Mechanisms of apical–basal axis orientation and epithelial lumen ...
May 1, 2015 · We provide an overview of the molecular mechanisms required to construct and orient the apical lumen. The establishment and orientation of an apical–basal polarity axis is …
Apical–basal polarity and the control of epithelial form and function
Apr 19, 2022 · Apical–basal polarity is essential for epithelial cell form and function, as it determines the localization of the adhesion molecules that hold the cells together laterally and …
Transcriptional Control of Apical-Basal Polarity Regulators
Epithelial cells exhibit apical-basal polarization with an outwards-facing apical membrane domain and a basal side that faces the extracellular matrix of the basal lamina. The lateral domains of …
Organization and execution of the epithelial polarity programme
Mar 21, 2014 · Epithelial cells require apical–basal plasma membrane polarity to carry out crucial vectorial transport functions and cytoplasmic polarity to generate different cell progenies for …
Local auxin sources orient the apical-basal axis in ... - PubMed
Dec 16, 2013 · Plants utilize directional, cell-to-cell transport of the growth hormone auxin to generate an asymmetric auxin response that specifies the embryonic apical-basal axis. The …
Pole position: How plant cells polarize along the axes - PMC
Each filament possesses a single basal–apical axis, and the canonical Physcomitrium PINs polarize along this axis, accumulating preferentially toward the apex of the filament. PINs are …
Cell Deformation Signatures along the Apical-Basal Axis: A 3D …
Jan 29, 2025 · This formalism yields analytical solutions predicting cell cross sections along the entire cylinder axis. Deconvolution microscopy experimental data confirm the significant and …
We provide an overview of the molecular mecha-nisms required to construct and orient the apical lumen. The establishment and orientation of an apical–basal po-larity axis is instrumental for …
Apical and Basal Matrix Remodeling Control Epithelial …
Jul 2, 2018 · We show that elongation of the wings and legs of Drosophila involves a columnar-to-cuboidal cell shape change that reduces cell height and expands cell width. Remodeling of the …
Efflux-dependent auxin gradients establish the apical-basal axis …
Nov 13, 2003 · Here we show that the first manifestation of the apical-basal axis in plants, the asymmetric division of the zygote, produces a basal cell that transports and an apical cell that …
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