Chromatography Online
Researchers employed a gas chromatography-mass spectrometry (GC–MS)-based metabolomic approach combined with sophisticated statistical methods to identify metabolic biomarkers in coronary heart disease (CHD), hypertension-comorbid CHD, depression-comorbid CHD, and type 2 diabetes mellitus (T2DM)-comorbid CHD to provide an objective diagnostic method and help identify metabolomic signatures ...
About LCGC International - Chromatography Online
Jan 1, 2019 · Founded in 1983, LCGC International is the leading provider of digital and print content to the separation science market, enhancing the productivity, efficiency, and the overall value of separation techniques globally. With our commitment to editorial excellence, we have pioneered innovation across a broad portfolio of digital and print platforms.
The Flame Ionization Detector - Chromatography Online
Dec 1, 2005 · John V. Hinshaw Although these ionization detectors share several features, their implementations differ significantly. Detector performance characteristics (sensitivity, minimum detectable quantity, linearity, and selectivity) are affected strongly by the type of ionization mechanism, the internal electrode arrangement, and the electronics.
Certificate of Analysis (CoA) and Calculations for Small-Molecule …
Jun 10, 2024 · Case Studies from an Early-Phase Small-Molecule Development Project: Background Information. A case study from my experience as a chemistry, manufacturing, and controls (CMC) analytical team lead supporting an early-phase small-molecule oncology drug development project was used to illustrate how CoAs expedite quality documentation of testing methods and results.
Ultraviolet Detectors: Perspectives, Principles, and Practices
Oct 1, 2019 · Requirements and Desirable Characteristics of UV Detectors. Table II summarizes the requirements and desirable characteristics of a modern UV detector (VWD or DAD), followed by a discussion of historical perspectives, optical designs, operating principles, and common operation and maintenance procedures.
LCGC North America - Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
LCGC Europe - Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
LCGC International - Chromatography Online
Practical advice, tutorials, and peer-reviewed research on liquid chromatography (HPLC), gas chromatography (GC), mass spectrometry (MS) and related techniques.
The Limit of Detection - Chromatography Online
Feb 1, 2009 · The concept of the limit of detection (LOD) has been, and still is, one of the most controversial in analytical chemistry. The multiple definitions and calculation methods proposed have contributed to this situation. Although in the last years, several international organizations, such as ISO or IUPAC, have tried to reach a consensus in their definitions and have issued guidelines for the ...
Chromatography Fundamentals, Part VIII: The Meaning and …
Nov 1, 2019 · The effectiveness of a separation can be quantified by measuring the resolution. This article explains the factors influencing resolution and the equation for predicting the required number of theoretical plates to obtain a given esolution.