Lacunar infarcts are small infarcts in the deeper parts of the brain (basal ganglia, thalamus, white matter) and in the brain stem. Lacunar infarcts are caused by occlusion of a single deep penetrating artery. Lacunar infarcts account for 25% of all ischemic strokes. Atherosclerosis is the most common cause of lacunar infarcts followed by emboli. 25% of patients with clinical and radiologically defined lacunes had a potential cardiac cause for their strokes. | Neurology
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Aazer Nawab on Instagram: "Hypertension causes lacunar infarcts through a chain of structural changes in the deep penetrating arteries of the brain (lenticulostriate arteries, thalamoperforators, pontine perforators). 1)Chronic High BP → Lipohyalinosis •Constant high pressure damages the endothelial lining. •Plasma proteins leak into the vessel wall. •Smooth muscle gets replaced by hyaline material. This process is called lipohyalinosis. Result: the vessel wall becomes thick, weak, and narrowed.
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